Traditionally, western medicines are commonly used to treat Lupus Nephritis due to the fast and high effect. However, no matter what kind of treatment is taken, the aim is the same that is to inactivate lupus factor and relieve the discomforts brought by this disease.
Patients with light SLE but with immunoserology abnormality can choose NSAID medicine to relieve clinical symptoms if their urine test results is relative normal and glomeruli is also normal or only have slight damage through biopsy results. In this case, glucocorticoid or cytotoxic agents is not commonly used, but regular and close observation on the illness condition is necessary. If there is abnormal item in urine test results, and there are also glomeruli focal segmental membrane proliferation as well as segmental necrosis and crescent, glucocorticoid in small or middle dosage can be taken and cytotoxic agents can also be taken rationally.
For patients with serious SLE accompanied by acute nephritis syndrome or progressive nephritis syndrome, standard hormone treatment as well as CTX or Methylprednisolone should be taken if diffusive proliferative glomerulonephritis or crescentic glomerulonephritis, accompanying with kidney function progressive decline can be found. If the above method is not so effective, plasmapheresis should be considered. If acute renal failure or hear failure occur, dialysis is necessary for patients to save their life.
Immunoadsorption is a good method to for Lupus Nephritis patients, which can also relieve related symptoms effectively. According to different individual body condition and illness condition, the treatment will also be different to each other in order to make sure each patient can get a relative good effect. Since there is damage in kidney for Lupus Nephritis patients, kidney function will also decline. Therefore, when Lupus Nephritis patients choose medicine, they should follow doctor’s advice closely.
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